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Kernel hardness is mainly controlled by one major genetic locus on the short arm of chromosome 5D in bread wheat.
Recent genome-wide association studies of HIV-1 clade B exposed cohorts have confirmed that HLA-B, which is the most polymorphic locus in the human genome, is the major genetic locus contributing to immune control of viraemia.
The upper limit of 0.6 is somewhat surprising given that direct effects from Prnp (the major genetic locus for the disease) have been excluded by experimental design.
The authors concluded that the major genetic locus that controls the altered olfactory response between the Z and E races did not result in a rewiring of the olfactory neurons, rather, the mechanisms must be located at the periphery.
Fuji et al. [ 24, 25] found a single major genetic locus associated with lymphocystis disease resistance in Japanese flounder and succeeded in commercially producing a lymphocystis disease-resistant strain by marker-assisted selection (MAS).
For instance, a single major genetic locus associated with lymphocystis disease resistance has been detected and its candidate gene tlr2 identified, making the development of a lymphocystis disease-resistant strain of Japanese flounder possible by marker-assisted selection.
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However, there was predominance of resistant progenies over susceptible ones, indicating the presence of major genetic loci in the population governing resistance.
Mating isolation between the Z- and E-races of ECB is controlled by a few major genetic loci, including pher and resp, controlling female blend production and male response, respectively [12] [15].
Four major genetic loci controlling tolerance to high soil B have been identified in the landrace barley, Sahara 3771.
Our results showed excluding LRTOMT, TMHS and TMIE as major genetic loci underlining SNHL in a cohort of 100 patients from the Western region of Saudi Arabia.
The major genetic loci conditioning red bulb colour (R) and fructan content (Frc) were located on this map by QTL analysis.
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