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Type A viruses are the ones with the potential to cause pandemics, because they can undergo major genetic changes suddenly and emerge in forms to which most people have little or no resistance.
The absence of major genetic changes during the second stage of speciation can be understood by considering the role of natural selection, which directly promotes the evolution of prezygotic RIMs during the second stage, so that only genes modifying mate choice need to change.
Changes in diet over time can modify the jaw muscles in ways that also alter skull shape, without major genetic changes, Larsen argues.
Sometimes, the prospects for domestication can depend on the probability of major genetic changes (such as genome duplications and/or hybridizations, as in polyploid wheat), but it also may be as simple as the nature of the genetic system underlying specific features.
Critics worry about the unforeseen consequences of major genetic changes being passed on for generations.
These virus strains had undergone major genetic changes for which the population did not possess significant immunity.
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Four months later, the TIGR scientists were elated when they discovered the morph had a major genetic change in its genome, known as an indel, short for insertion or deletion of DNA.
Gene expression levels vary over the course of infection; tremendous numbers of genes are differentially expressed in the first 48 hrs post-infection, suggesting a major genetic change that likely precedes a life-stage change.
Because of this property, it is one of the most frequently amplified genes in tumors, a major genetic change that leads to uncontrolled proliferation of cancer cells (Dang, 2012).
The results show, in agreement with published clinical data, that the major genetic change affecting 5FU response is mismatch repair status, thus validating the appropriateness of our method of analysis.
Similar to ERα, the results confirm that in the high percentage of breast cancers that express AR, gene amplification does not seem to be a major underlying genetic change.
More suggestions(15)
large genetic changes
fundamental genetic changes
major genetic modifications
major genetic alteration
large scale genetic changes
major genetic clades
major genetic maps
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major territorial changes
major genetic strains
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major genetic aberrations
major genetic causes
major genetic abnormalities
major genetic mutations
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