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We used GO enrichment analysis to identify the major gene groups affected by mycorrhization.
There were also 2 major gene groups, one with 17 genes and the other with the remaining 7 seven genes.
Gene microarray analysis confirms that the central functions of AR in myometrial cells are to regulate cell cycling and apoptosis through three major gene groups involving the epidermal growth factor (EGF) signaling, RNA splicing and DNA repair processes.
To delineate cogent trends within this complexity, we identified major gene groups that exhibited a normalised enrichment at exponential, transitional or stationary phases across the S.erythraea life cycle (Additional file 1: Figure S3A-C, S4A-C).
One of the major gene groups codes transcriptional regulators involved in anatomical development and may be involved in the various levels of lineage-specific evolution such as vertebrates, mammals, primates, and rodents.
In the present study, two major gene groups, ATP-regulated IRK and G-protein-activated IRK, of which gene branches were placed quite distantly on the phylogenetic tree derived from the IRK AA sequences, were found to be physically correlated closely and franked anti-tandemly as pairs on the individual chromosomes.
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(E ) Major gene functional groups from genes activated above fivefold by TAF7L in C2C12 cells post adipogenic induction through gene ontology analysis.
(D ) Average TAF7L binding signal strength (vertical axis) on the core promoters (500 bp from TSS) and proximal enhancers (500 bp to 5 kb from TSS) of three major gene expression groups as in (C ).
In this study, we applied the YTH approach to three major target gene groups.
One of the major corpus gene groups (C4; containing 640 genes) contained the genes whose expression was characterized by loss of expression in the atrophy patients.
Then the parallel but independent functional evolution during long archeological history could occur in the gene pairs deriving, respectively, two major distinct gene groups as a result of mutual and physical constraining in the gene regulatory regions.
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