Sentence examples for major gene effect from inspiring English sources

Voss, S. R. & Shaffer, H. B. Adaptive evolution via a major gene effect: paedomorphosis in the Mexican axolotl.

Hinney, A. et al. Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

At the MC4R locus, common SNPs are associated with polygenic forms of obesity and variants leading to a reduced MC4R function entail a major gene effect for obesity.

Some results support the idea that morphological evolution can occur basically by a small proportion of major effect mutations in structural, developmental or regulatory key genes (major gene effect hypothesis [2], [3].

Thus, the commingling distributions of the two populations are better explained by a mixed distribution than a single one and are compatible with a possible major gene effect (fig. 1).

When pleiotropic effect is present, bivariate analysis is more powerful than univariate analysis unless the residual correlation is high and in the same direction to the correlation of major gene effect, coinciding with the findings in linkage studies [27].

For example, there may be major gene effects that may be largely or entirely nonadditive, temporal or developmental trends, and gene-gene (epistasis) and gene-environment interactions.

For example, there may be major gene effects that are largely or entirely nonadditive, temporal or developmental trends, and gene gene (epistasis) and gene environment interactions.

This review examines the influence of sheep genotype on meat quality traits where genotype includes breeds, cross-breeds and major gene effects.

Despite strong evidence of genetic effects for vulnerability to alcohol dependence, linkage-based analyses failed to identify major gene effects.

These results indicate a substantial genetic effect and suggest major gene effects for the trait.