Sentence examples for major gene defect from inspiring English sources

Our group has focused on a single major gene defect with pleiotropic effects, one of which manifests bipolar disorder.

Conversely, it is possible that neutral or silent variants or polymorphisms in the 15 genes sequenced here or in other genes might serve as disease modifier alleles with another major gene defect occurring simultaneously [36].

The major single gene defects are uncommon while a number of important environmental factors have been substantiated.

The work "now gives us a more scientific basis" to question cloning, says Hans Schöler, a molecular biologist at the University of Pennsylvania School of Veterinary Medicine in Kennett Square, who earlier this year reported that most clones have a defect in a major gene involved in development.

The SLC36A2 (PAT2) gene was identified as the major gene responsible for iminoglycinuria, a renal defect characterised by reduced reabsorption of glycine, proline and hydroxyproline (Online Mendelian Inheritance in Man, OMIM: 242600).

Even then, a possible carrier of the gene defect may not be tested.

His electrocardiogram showed long-QT syndrome, and genetic testing revealed a gene defect known to cause the heart problem.

Sporadic or no major gene model.

Major gene without familial association model.

There were three major gene clusters.

Neither a chromosomal defect nor a single gene defect has been identified as the underlying cause.