Sentence examples for major functional targets from inspiring English sources

However, major functional targets that mediate the antimetastatic activity of miR-493 remain elusive.

These findings suggest that SLC2A3 is a major functional target of miR-106a involved in glioma cell glycolysis and proliferation.

Thus, MKK7 is a major functional target of miR-493, and its suppression thwarts liver metastasis of colon cancer cells.

There are two major functional subsets among the a1- α2 target genes identified in this analysis (Table 1).

The identification of the functional targets of positive selection, however, has been a major challenge in understanding the evolution of human beings.

Fyn represents a unique therapeutic target in AD as it is central to Aβ signal transduction, and has major functional interactions with Tau, thereby unifying the two major pathologies in AD.

However, because of the non-vital role and the likelihood of major functional redundancy in Plasmodium redox defence and ribonucleotide reduction, Plrx can largely be excluded as a valid target for antimalarial intervention strategies.

The other major functional changes are related to navigation.

"The major functional areas have been cloudified," he says.

They constitute the major functional part of the root system.

Fig. 2 The major functional modules of the PBL application.