In actual practice, the major functional classifications of patients with dyspnea are based on the degree of exertion.
The genes induced or repressed in PPV-infected protoplasts were annotated, assigned to a predicted function and classified into 12 different major functional categories using the Arabidopsis MIPS functional classification scheme.
The classification results according to 13 major functional categories are shown in Figure 3, and the detailed classification of each unigenes is listed in Additional file 2. Transcripts related to protein synthesis and cell structure represent the largest group of transcripts with known function in the apical cell, and both compose of 20.36% of the apical cell unigenes.
We provide a non-redundant dataset for the human membrane proteome and a qualitative functional classification for all major groups and families containing 6,718 proteins.
The gene distributions were compared by classifying the predicted protein products into major functional categories, according to the COG protein classification scheme (Figure S3).
However, the diagnostic interpretation of individual rare variants remains a major challenge, and may require accurate variant functional classification and the collection of large numbers of variant carriers.
Based on the Arabidopsis top hits, we obtained the GO annotations for the avocado unigenes, and WEGO software [ 23] was used to perform GO functional classification into the three major classes (Fig. 2; Additional file 1: Table S3).
Extension of this work into the area of vaccinology has suggested a classification of adjuvants into two major functional groups, those being dependent and independent of binding to TLRs [ 3, 4].
Whereas major challenges undoubtedly remain, particularly regarding data handling and the functional classification of variants, we suggest that these will be largely practical and not conceptual.
Phylogenetic analysis revealed that the candidate CstyEsts clustered within all three of the major functional groups of the esterase gene family (based on the classification system of [ 47]).
