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Polyphenol oxidases are the major functional candidate genes for the enzymatic browning reaction.
We propose that VvAGL11 is the major functional candidate gene for seedlessness, and we provide experimental evidence suggesting that the seedless phenotype might be caused by variations in its promoter region.
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A MADS-box ovule identity gene (VvAGL11) was proposed as the major positional and functional candidate gene for stenospermocarpy and tested for usefulness in marker-assisted selection [ 24, 25].
We consider the ortholog of the seven-up receptor as the top functional candidate for the second major QTL (on chromosome 6) because seven-up is a nuclear receptor that can inhibit ecdysteroid signaling [ 47], controls cell proliferation [ 48], and interacts with Krüppel [ 49], a gene that has been implied in reproductive regulation in workers of honey bees and bumble bees [ 50].
Phylogenetic analysis revealed that the candidate CstyEsts clustered within all three of the major functional groups of the esterase gene family (based on the classification system of [ 47]).
Because common promotor variants frequently have major influence on the expression level of the gene product, rs1341402 is an excellent functional candidate variant in the promotor region of G72.
To identify deficiencies in any major functional cell pathways that may provide further evidence of cellular hyporesponsiveness, we used microarrays to identify candidate genes and pathways that may be dysregulated in schizophrenia.
The other major functional changes are related to navigation.
"The major functional areas have been cloudified," he says.
They constitute the major functional part of the root system.
Fig. 2 The major functional modules of the PBL application.
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