Sentence examples for major expression changes from inspiring English sources
Out of the 25 genes expressed only in the central domain, 3 (12 %) will exhibit major expression changes, or terminate their expression (Table 4, first row).
However, subset D, which shows the strongest response upon these exposures, did not include any Th2-associated cytokines, suggesting that the major expression changes take place downstream of Th2 cytokine signaling.
Interestingly, reciprocal trends bend at similar age, suggesting that major expression changes are at defined time points.
To extrapolate the age at which major expression changes occur, we applied k-means clustering with absolute correlation as metric, which clusters reciprocal trends together.
Figure 6 shows an overview of the major expression changes that we interpreted as caused by mycorrhization, as annotated by MapMan software [ 85].
All these observations are congruent with our previous findings in primary cultures of striatal neurons expressing mHtt, where loss of Ip preceded that of Fp (17), and was seen while many other mitochondrial proteins showed no major expression changes.
Moreover, since the timing of major expression change corresponds to the transition from prespawning/spawning to sexually regressed female goldfish, the high expression status of these genes around May, therefore, should be required for the fish spawning period.
In this study, we identified a set of miRNA that are expressed in normal breast epithelium and found that major miRNA expression changes occur at the transition from normal to DCIS epithelium, thereby defining a set of putative oncogenic and tumor suppressor miRNA that are dysregulated at the preinvasive stage of breast cancer.
Remarkably PCA of these data showed that the major gene expression changes induced by these stimuli were extremely similar, and markedly different to changes induced by LPS.
To capture major gene expression changes common to G144, G166 and G179, we set strict criteria on fold changes and tag counts (see Materials and methods).
These studies revealed major gene expression changes during seed filling and desiccation, along with distinct expression patterns related to carbohydrate metabolism, lipid biosynthesis and storage protein accumulation.
