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There is however little evidence for major evolutionary innovation within the KAP-β family post-dating the LECA.
A major evolutionary innovation of eukaryotes for chromosome segregation relies on the assembly of a complex bipolar structure, the mitotic spindle, and the linkage of a specialized region of chromosomes, the kinetochore, to spindle microtubules (MTs), allowing the migration of genetic material to spindle poles.
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If, say, hand shape could not change independently of foot shape, selection could not make back feet suitable for walking while leaving the ape with usable hands.So for Darwin to think that natural selection explains major evolutionary innovations, he had to bet on the amount and kind of variation that typically exists in lineages.
If confirmed, the find reinforces the idea that major evolutionary innovations occurred in bursts.
Moreover, disturbance-prone environments might be an important source of major evolutionary innovations (Rice 1990).
Specifically, these introductions of new gene flows can inform us about major evolutionary innovations.
Major evolutionary innovations are expected to be accompanied and, at least partly, caused by the emergence of founder genes.
Symbiotic relationships have contributed to major evolutionary innovations, the maintenance of fundamental ecosystem functions, and the generation and maintenance of biodiversity.
Although transposons are often regarded as junk DNA, a growing body of evidence indicates that they are behind some of the major evolutionary innovations.
This distal-proximal microspore polarity transition in development contrasts with the evolutionary shift from a proximal to a distal aperture that has been long regarded as one of the major evolutionary innovations in seed plants [ 52].
A substantial excess of intron gains has been detected only for those intervals of eukaryotic evolution that are associated with major evolutionary innovations, such as the origin of eukaryotes and animals [ 5, 12- 14].
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