Sentence examples for major epithelial cell from inspiring English sources
The loss of Clara, ciliated and goblet cells in response to Sox2 deletion are consistent with the proposed role of Clara cells as progenitor cells in bronchioles, and show that Sox2 is necessary for normal proliferation and differentiation of the major epithelial cell types lining the bronchioles (Fig. 8).
There are three major epithelial cell types in the airways: ciliated cells, Clara cells, and goblet cells.
These results suggest that two different assemblies of Notch receptors coordinate the numbers and distribution of the major epithelial cell types in the conducting airway during lung organogenesis.
Alveolar type-2 (AT2) cells, the major epithelial cell type in V600EBRAF-driven lung tumours (Dankort et al, 2007), were also freshly isolated from BVE mice at 10 weeks p.p. using the fractionation method (Supplementary Fig S2).
There are two major epithelial cell lineages in the mammary gland (MG), luminal lineage (including ductal and alveolar luminal cells), and basal lineage (the mature cell type in the basal lineage is myoepithelial cell).
This work revealed that many gastric glands showed a loss of transgene function in all major epithelial cell types, consistent with clonal expansion of a single mutation, therefore indicating the existence of multipotent gastric stem cells.
In fish gills, the two major epithelial cells, pavement cells (PVCs) and mitochondria-rich cells (MRCs), are known to play key and complementary roles in ion transport at the interface.
Comparing the four major epithelial histologic cell types, endometrioid has a statistically significant increase in 3-year disease-specific survival compared with the other histologies as seen in Table 2 and Figure 2 (P=0.015).
Thus, the numbers and distributions of the three major lung epithelial cell types are established by two distinct Notch-dependent mechanisms: Notch2 signaling controls Clara cell number, and three Notch receptors in SPNC cells activate Hes1 to control pNEBs.
The carbohydrate-rich glycoproteins ("mucins") and lipids of the mucous layer are produced by submucosal glands and, particularly in species with low numbers of such glands, the second major surface epithelial cell type, broadly designated "non-ciliated cells".
Here, we concentrate on the major surface epithelial cells.
