Sentence examples for major elimination pathways from inspiring English sources

Exhalation and excretion in the urine are the major elimination pathways after oral exposure.

At normal dosage, the major elimination pathways of APAP involve glucuronide and sulfate conjugation.

It was also able to characterize the contribution of major elimination pathways with respect to urinary recovery of each metabolite following both 5 and 20 mg/kg i.v. infusion of APAP (see Supplementary Table S2 online).

37– 40 There are two major elimination pathways for mavrilimumab: intrinsic clearance by the reticuloendothelial system in the same way as that for an endogenous IgG, and elimination by the target antigen receptor (GM-CSFR-α mediated clearance).

Formation of noroxycodone by CYP3A4 is the major elimination pathway of oxycodone [ 35].

Finally, the kidneys are a major elimination pathway for many antineoplastic drugs and their metabolites.

45 Decitabine is inactivated through its major elimination pathway by liver cytidine deaminase.

The results emphasized the role of renal metabolism of dapagliflozin to D3OG, which is the major elimination pathway of dapagliflozin.

Since urinary excretion is a major elimination pathway for many antineoplastic drugs, renal impairment may alter the excretion rate of chemotherapeutic agents.

Metabolism (primarily glucuronidation via UGT1A9) is the major elimination pathway of dapagliflozin: ~60%, and <2% of an administered dapagliflozin dose is recovered from urine as D3OG and dapagliflozin, respectively.

Radioactive-labelled capecitabine studies have shown that 99.5% of radioactivity is recovered from urine (Judson et al, 1999), indicating that renal excretion is the major elimination pathway for capecitabine and its metabolites.