Sentence examples for major effectors of from inspiring English sources

The major effectors of these modifications are the chromatin modifier enzymes, highly specific proteins that catalyze the addition or removal of functional groups to DNA or histone tails.

These observations suggest that ETS1 and ETS2 are major effectors of RAS/MAPK signaling, and thus can be alternative targets for the RAS/MAPK pathway.

In this article, we have proposed transcription factor ETS1 and ETS2 as alternate therapeutic targets because they are major effectors of RAS/MAPK signaling.

Applying Mosaic-seq to 71 constituent enhancers from 15 super-enhancers, our analysis of 51,448 sgRNA-induced transcriptomes finds that only a small number of constituents are major effectors of target gene expression.

Gliadin peptide P31 43 can increase IL-15, one of the major effectors of innate immunity in CD on CaCo-2 cell surface, not affecting mRNA or protein levels, but increasing the recycling of the complex IL-15/IL-15 IL-15/IL-15 IL-15/IL-15embreceptor 15, 16].

Together with recruited macrophages, resident microglial cells are the major effectors of the brain immune response.

The AM, a major effector of early resistance to bacterial infection, can be affected by ventilation [16].

A major effector of neutrophils with a critical role in CF is neutrophil elastase (NE), a serine protease composed of 218 amino acids.

By comparing noxE- and fdh-harbouring strains, the form of NADH, rather than NAD+, was the major effector of furfural tolerance.

Upon tissue injury, the activity of YAP, the major effector of the Hippo pathway, is transiently induced, which in turn promotes expansion of tissue-resident progenitors and facilitates tissue regeneration.

The complement system is the major effector of the humoral arm of the immune system.