Sentence examples for major effector regulating from inspiring English sources

In contrast, angiotensin II, the major effector regulating blood pressure, can be synthesized by alternative pathways (Wolny et al. 1997).

Additionally, PI3K is the major effector of Pdgfra regulating craniofacial development in mouse (Klinghoffer et al., 2002).

And some researchers have reported that VEGFR-2 can also be expressed on lymphatic endothelial cells, while its expression levels were less than VEGFR-3 in lymphatic ECs, because VEGFR2 is the major effector of angiogenesis and regulates blood vessel growth of vascular ECs, not lymphatic ECs [ 35– 35].

Results from our study identify HK2 as a major effector of PHLPP-mediated regulation of glycolysis.

As a major effector in the Wnt oncogenic pathway, β-catenin is thought to be regulated mainly at the protein level, and mechanisms for transcriptional regulation of β-catenin have received little attention to date.

A further role for Cdc42 as a major effector of polarisation and cytoskeletal organisation was also found, with expression of the active form of this protein being regulated by TGFβ and CCN2 together.

Caspase 3 is one of the major effector caspase in caspase cascade which ultimately induces apoptosis.

The gene rosy regulates lipid droplet coupling to the plasma membrane during lipid secretion (244), and the mammalian homolog of white ABCG1 is a major effector in lipid trafficking (245).

CD3+CD56+ cells are the major effector population of CIK cells.

Antibody secretion is the major effector function of B cells.

Rab9A and its effectors regulate recycling of mannose 6-phosphate receptors from late endosomes to the trans Golgi network.