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It may not sound like a huge deal, but just as very small tweaks on Google can have a major effect, a minor change to YouTube's design may well change the way people use the site.
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In some instances, however, selection may act on a new single variant that has a major effect on a phenotype of interest4.
A major effect is a labor shortage in Alsace.
Segmental duplication is a major effect at a higher observed SNP minor allele frequency.
Nothing would have such a major effect for so low a cost.
Performance measures have a major effect on cardiovascular outcomes: a review.
A major effect of astrocytes in a lesion environment is through expression of extracellular matrix molecules.
"It has a major effect on the morale of a football club.
A: Shouldn't be a major effect here.
Sen is a rare example of an intellectual who has had a major effect on politics.
There remains a broad expectation that a lack of agreement will deliver a "major effect" on the economy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com