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While this formulation is straightforward, it bears some major drawbacks preventing computability for practical scenarios.
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Rapid degradation of magnesium (Mg) alloys is the major drawback preventing these materials from being applicable as tissue engineering scaffolds.
There are also very specific drawbacks preventing access to LAMB for VL.
However, a major drawback that prevents surface-based NP dimer PNR sensors from being widely used is the low efficiency of their synthesis.
Another drawback preventing immediate applications may be the high concentration of MLE used in this study.
This also does not prevent other major drawbacks of this PPG for the release of alcohols, which is slow (vide supra), and of amines, which undergo condensation with the nitrosoaldehyde side-product, leading to a stable imine; however, the latter reaction can be avoided by the addition of carbonyl scavengers, such as semicarbazide hydrochloride.
One of the major drawbacks of LMA is inability to prevent a generation of negative and off-limits values during the fitting process.
A major drawback of preventive antibiotic therapy is the potential induction of antibiotic resistance.
However, its major drawbacks, including high write energy and limited write endurance, have prevented its usage as a drop-in replacement of DRAM technology.
We propose that reducing TMA formation in the gut by converting it to an inert molecule could be used to prevent or limit these human diseases, while avoiding the major drawbacks of other clinical interventions.
However, major drawbacks such as poor rate capability owing to insufficient electronic and ionic conductivities [19 21] have prevented their use in commercial applications.
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CEO of Professional Science Editing for Scientists @ prosciediting.com