Sentence examples for major downstream output from inspiring English sources

The DAF-16/FOXO transcription factor is the major downstream output of the insulin/IGF1R signaling pathway controlling C. elegans dauer larva development and aging.

ADP-ribosyltransferases (ARTD1 16) have emerged as major downstream effectors of NAD+ signaling in the cell.

However, the decision to rapidly expand the electronic availability of healthcare records has some major downstream consequences.

This represented the end of the last major "downstream" use of the Gulf brand by Chevron.

ROCK is a major downstream effector of RhoA GTPase.

Akt is a major downstream effector of the IGF1R in mammals and in zebrafish [19].

XBP-1 splicing is a major downstream target of the IRE1 signaling.

The output of the upstream signaling was the total phosphorylated Shc, and the downstream output was the total phosphorylated ERK.

The major downstream target of PI3K/AKT activation is mTOR.

Phosphorylation of the RR leads to activation of the downstream output domain that elicits specific responses.

11 A major downstream effector of AKT is mTOR complex1 (mTORC1); its downstream targets, such as ribosomal S6K1, control protein synthesis.