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The only major downside is that the vast majority of the free web videos it finds will not play through Google TV.
The major downside is the lack of bathroom facilities.
Look at his doodles on the original typescript!" Yes, the Clockwork Orange app's major downside is that it will turn you into a bore.
"The major downside is that you have to be watchful," said Don Nielsen, senior vice president for the American Hospital Association.
One major downside is that while campus students can enjoy a leisurely walk or cycle to lectures, most London students join the hordes in their commute across the city on packed tubes.
"Bipolar is absolutely being overdiagnosed in children, and the major downside is that people then think they have a solution and are not amenable to listening to alternatives," which may not include drugs, said Dr. Gabrielle Carlson, a professor of psychiatry and pediatrics at Stony Brook University School of Medicine on Long Island.
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A major downside are increased rates of wound complications compared to postoperative RT.
The major downsides are only that it is time-consuming and somewhat painful, especially in sensitive areas.
While I really dig the fact that the keyboard base actually seems to have some weight to it (imagine trying to use the Surface's floppy physical keyboard on your lap), there is of course one major downside: it's going to be a hefty little convertible.
The major downside however, is that eType currently only supports Windows XP and above.
One major downside howver is that this first iteration won't appear running on the iPhone.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com