Sentence examples for major dose limiting from inspiring English sources

Importantly, while PNS neurotoxicity and concomitant chemotherapy-induced peripheral neuropathy (CIPN) are among major dose limiting barriers in achieving therapy goals, CIPN is partially reversible during post-treatment nerve recovery.

Thrombocytopenia was the major dose limiting toxicity followed by neutropenia.

The major dose limiting toxicity (DLT) is myelosuppression, predominantly neutropenia, which is usually short lasting, dose dependent and non-cumulative (Extra et al, 1993; Tomiak et al, 1994; Pronk et al, 1998).

In addition to the kidneys, the bone marrow is a major dose-limiting organ.

Vascular leak syndrome (VLS) is the major dose-limiting toxicity of immunotoxin therapy.

While radiotherapy is very effective in eradicating disease, one of the major dose-limiting factors is the tolerance of the adjacent uninvolved tissue [2 6].

Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting and persistent consequence of numerous classes of antineoplastic agents, affecting up to 30%40%% of patients.

Radiation pneumonitis (RP), which represents the acute phase of radiation-induced lung injury, is the major dose-limiting toxicity in radiotherapy for NSCLC.

Nephrotoxicity is the major dose-limiting toxicity.

The major dose-limiting toxicity was peripheral neuropathy (PN).

The major dose-limiting factor for carboplatin therapy has been recognised to be thrombocytopenia.