major disposition

USAGE SUMMARY

The phrase "major disposition" is correct and usable in written English.
It can be used in contexts where you are discussing significant attitudes, tendencies, or arrangements regarding a particular subject or situation. Example: "Her major disposition towards teamwork has greatly influenced the project's success."

✓ Grammatically correct

Science

News & Media

Formal & Business

Human-verified examples from authoritative sources

Exact Expressions

1 human-written examples

Due to the lack of intestinal transporter data under cirrhotic conditions at this time, assuming liver is the major disposition organ, and no change of the intestinal transporter activity, the absorption parameters are kept the same for the healthy and liver cirrhosis groups.

CPT: Pharmacometrics and Systems Pharmacology

Human-verified similar examples from authoritative sources

Similar Expressions

59 human-written examples

Of the Big five personality, neuroticism and extraversion are the two major dispositions reflecting individual differences in the degree to which one experiences overall negative and positive affect, respectively.

BMC Psychiatry

This would indicate that renal function plays a major role in the disposition of SN-38G and that the elimination of this metabolite is a determinant of its plasma concentration as important as its formation from SN-38.

British Journal of Cancer

Mr. Major contributes his disposition: he makes serious juice fun.

The New York Times - Food

The abstracts include information on patient demographic characteristics, ZIP code of residence, the principal diagnosis (defined as the condition chiefly responsible for the hospitalization, by ICD-9-CM codes), up to 24 additional diagnoses, major procedures, and disposition.

Diabetes Care

Our observations have the following implications: a) the visualization of red fluorescence suggest aggregation of a large number of QD705 nanocrystals in situ because fluorescence from one or a few particles of QD705 would have been invisible under the microscope; b) a major mechanism of disposition of QD705 involves mononuclear phagocytic system and organs.

Environmental Health Perspectives

The SLC22 family of transporters is mostly composed of non-selective transporters, which are expressed highly in liver, kidney and intestine, playing a major role in drug disposition.

British Journal of Pharmacology

The most affected in the xenobiotic metabolism group, the CYP3A genes, play major roles in metabolic disposition of wide variety of drugs [ 55].

BMC Genomics

The pharmacokinetic properties of i.v. ARS overall were similar in pregnancy and in the same women post partum in a healthy state and neither pregnancy nor disease had a major effect on the disposition of ARS or DHA.

British Journal of Clinical Pharmacology

It is now time to rethink the historical assumption that all high-potency sweeteners are inert compounds devoid of physiological effects other than peripheral taste responses but rather that some of these molecules can interact with transporters and cytochrome P450 enzymes that play a major role in the disposition of drugs.

Chemical Senses

"Clearly, actions beyond resolving our operational issues are required, including major cost reductions, asset dispositions and a review of the dividend level," Paul A. Allaire, Xerox's chairman, and Anne M. Mulcahy, its president, said in a joint statement yesterday.

The New York Times

Expert writing Tips

Best practice

In scientific or technical writing, use "major disposition" to describe the primary way a substance is handled or distributed within a system. For example, "The major disposition of the drug is through renal excretion."

Common error

Avoid using "major disposition" when you actually mean "predisposition". "Disposition" refers to a current state or tendency, while "predisposition" indicates a susceptibility or inclination towards something in the future. For example, use "genetic predisposition" instead of "genetic major disposition".

Linguistic Context

The phrase "major disposition" functions as a noun phrase where the adjective "major" modifies the noun "disposition". This phrase typically describes a significant tendency, characteristic, or arrangement, as confirmed by Ludwig.

Expression frequency: Common

Frequent in

Science

58%

News & Media

29%

Formal & Business

13%

Less common in

Encyclopedias

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

The phrase "major disposition" is a grammatically sound and frequently employed expression used to denote a significant tendency, characteristic, or arrangement. Ludwig AI confirms its correctness and usability across various domains. Predominantly found in scientific, news, and formal contexts, it serves to emphasize the primary or most important aspect of a subject. Related phrases include "primary inclination" and "significant tendency". When employing this phrase, ensure it aligns with the intended meaning and isn't confused with similar terms like "predisposition", which indicates a susceptibility rather than a current state.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

main inclination

Similar to "primary inclination" but uses "main" to convey significance.

primary inclination

Replaces "disposition" with "inclination" emphasizing a natural tendency or preference.

significant tendency

Substitutes "disposition" with "tendency", focusing on a pattern of behavior or thought.

key characteristic

Replaces "disposition" with "characteristic", highlighting a defining attribute.

chief characteristic

Highlights a fundamental trait, swapping "disposition" for "characteristic".

principal arrangement

Emphasizes the main way things are organized or placed, using "arrangement" instead of "disposition".

primary attribute

Uses "attribute" to denote a quality or feature, similar to "characteristic".

dominant attribute

Focuses on the most influential quality, replacing "disposition" with "attribute".

significant arrangement

Similar to "principal arrangement" but uses "significant" to convey importance.

central tendency

Highlights a statistical or common behavior, substituting "disposition" with "tendency".

FAQs

How can I use "major disposition" in a sentence?

You can use "major disposition" to describe a significant tendency or arrangement. For example, "The liver is the major disposition organ for this drug" or "Her "optimistic disposition" helps her cope with stress".

What's a good alternative to "major disposition"?

Alternatives include "primary inclination", "significant tendency", or "key characteristic", depending on the specific context.

When is it appropriate to use "major disposition"?

It's appropriate when you want to emphasize that a particular tendency, arrangement, or characteristic is the most important or influential one in a given situation. This could be related to a person's character, a process, or the handling of resources.

Is "major disposition" the same as "predisposition"?

No, "major disposition" and "predisposition" have different meanings. "Major disposition" refers to a current, significant tendency or arrangement, while "predisposition" refers to a susceptibility or inclination towards something that may happen in the future.