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A major discovery arising from the use of these platforms is the importance of de novo mutations (that is, acquired mutations in the offspring) in psychiatric disorders such as intellectual disability (ID) [ 3- 5], autism [ 6- 10] and schizophrenia [ 11- 16].
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The major challenge in serum SEPs discovery arises from its extraordinary complexity in protein composition with the addition of post-translational modifications (PTMs) and protein variability, as well as the great concentration range (more than ten orders of magnitude) (Anderson and Anderson 2002; Omenn 2007).
Nocera's discovery arose from frustration.
As a result, the company claims rights to patents on 20 fundamental stem cell discoveries arising from early research.
CYP2D6 is a highly polymorphic gene, with new discoveries arising on a yearly basis.
"That was a major discovery".
Her major discovery was the late Walter Matthau.
It might be the harbinger of a major discovery.
"This is a major discovery that could rewrite science textbooks".
Neuroscientists' discovery of grid cells was hailed as a major discovery.
"It's been called the Holy Grail of cosmology," says Peiris, "It would be a real major, major, major discovery".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com