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The major difficulty faced by engineers working on higher bands is balancing the trade-off between bandwidth availabilities and rain attenuation issues.
In this study, we demonstrated that the major difficulty faced when using the full sequence similarity for the comparison of toxicity target orthologs to human proteins is due to variations in the length of the amino acid sequences.
Indeed, the major difficulty faced by investigations of fisheries-induced evolution in natural populations is that genetic changes and phenotypic plasticity are confounded in the phenotypic trait upon which most previous studies have had to rely.
The major difficulty faced by the archezoan hypothesis is that so far all candidate archezoa, such as Diplomonada, Parabasalia, and Microsporidia, have been shown to possess organelles derived from or, at least, related to mitochondria (hydrogenosomes, mitosomes, and others) as well as some nuclear genes of apparent mitochondrial (alpha-proteobacterial) origin [ 1, 6].
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But the major difficulty facing Catholic schools is hardly lack of financial support by the bishops — and certainly has nothing to do with the writers' non sequitur arguments about priestly celibacy.
But a major difficulty facing this approach is that the localization process is extremely sensitive to errors in the assumed propagation model and array calibration.
One major difficulty facing alethic relativists is to explain what "true for" actually means, and how "true for" should be understood as related to the more familiar absolutist truth predicate.
One major difficulty facing the assessment of ECM-guidance is the lack of a convenient way to determine if the cell motion observed is guided by the substrate or not; this is because most substrates that are used are coated homogenously with ECM.
A major difficulty facing authorities was the complexity of local land tenure arrangements.
The major difficulty facing clinicians is the identification of patients presenting with early stage CaP, who are likely to develop life-threatening disease.
The major difficulties faced in an embedded implementation are caused by the limitations in the hardware-resources available, and by the variability of the contexts where the system may operate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com