Sentence examples for major difficulty associated from inspiring English sources

One major difficulty associated with using an empirical model within the multi-step predictive control setting is that the model can be excessively extrapolated into regions of the state space where identification data were scarce or nonexistent, leading to performances far worse than predicted by the model.

The shallow water equations exhibit the major difficulties associated with the horizontal dynamical aspects of atmospheric modeling on the spherical earth.

Composition measurement has been one of the major difficulties associated with the composition control of distillation columns because the on-line analyzers still suffer from large measurement delays, high investment/maintenance costs and low reliability.

We demonstrate that large scale high quality graphene synthesis can be performed using atmospheric pressure chemical vapor deposition (CVD) on Cu and illustrate how this procedure eliminates major difficulties associated with the low pressure CVD approach while allowing straightforward expansion of this technology to the roll-to-roll industrial scale graphene production.

In another self-report study of students in English medium higher education programs in China, students identified comprehending lectures, understanding specialist vocabulary and writing in an appropriate academic style, as the major difficulties associated with studying through English as an L2 (Evans & Morrison, 2011 c.

Three major difficulties associated with changes due to development, MR imaging inconsistency, and cohort size confound the efforts of constructing infant atlases.

However, most of these techniques detect aneuploidy in the female and/or in the male germ line, and there are two major difficulties associated with the germ-line based procedures: (1) a limited number of the germline cells and (2) the long time course between the induction and the detection of the aneuploidy (Szabad and Bennettova 1986; Szabad et al. 1995).

However, a major practical difficulty associated with this approach is the large and erratic variability of quantile estimates with respect to the threshold value, which is not known a priori.

A major difficulty is associated with the respondent providing answers in pencil and paper form while involved in PA, particularly when it is intense [ 9, 19, 30, 31], and more generally, EMA is considered a more burdening and time-consuming approach for participants in comparison with retrospective methods, despite the potential benefits of real-time activity examination [ 25].

In particular, conditional knockout studies will become more abundant in the alcohol research community, allowing investigators to avoid some of the major interpretative difficulties associated with the conventional knockout studies that have dominated in the last 15 years.

The difficulty associated with recalling exposures is a major limitation of case-control studies designed to identify multiple potential risk factors.