Sentence examples for major differentiation factor from inspiring English sources

bam mutant GSC progeny successfully transit through the pre-CB stage (Fig. 1B), modifying chromatin into a ready to differentiate state; however, due to the lack of the major differentiation factor, Bam, these germline cells are not capable of proceeding to the differentiation program.

H2O2-responsive gene expression is manifested for both major differentiation factors of β-cells, PDX-1 and MafA (47).

Macrophages play a central role in IBD pathogenesis and are regulated by major differentiation factors such as CSF-1 (colony-stimulating factor 1) in homoeostasis and inflammation.

In humans, IL-5 is best characterized as a major maturation and differentiation factor for eosinophils [13].

Moreover, modulation of the neuroinflammtory response by genetically ablating myeloid differentiation factor 88 (MyD88), a major adaptor molecule essential for Toll-like receptor (TLR) signaling pathway, significantly delayed the progression of PC degeneration in the MPI118Q/118Q mice.

In addition, growth factor signaling is also a major differentiation impulse.

The NeuroD family of bHLH transcription factors, composed of three major members, such as NeuroD1 (BETA2), NeuroD2 (NDRF), and NeuroD6 (NEX1, MATH2, and ATOH2), acts as a differentiation factor for neural precursor cells in the developing central nervous system (CNS) [ 23].

Growth differentiation factor.

myeloid differentiation factor 88. Mycobacterium tuberculosis.

Our results indicate that macrophages constitute the major source of the pro-inflammatory cytokine IL-1β, the Th1-differentiation factor IL-18 and IL-27, which is implicated in the differentiation of several T-cell subsets.

Taken together, these results suggested that the inhibitory effect of matairesinol on osteoclast differentiation could arise from its potential to inhibit the expression of NFATc1, the key major transcription factor required for osteoclast differentiation.