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Anti-nuclear antibodies (ANAs) are highly prevalent and a major diagnostic marker for lupus.
Although many studies suggests role of Rv2623 as a major diagnostic marker for latent infection, there are no studies reported involving evaluation of Rv2623 in CSF of suspected latent and active TBM patients.
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Autoantibodies to glutamic acid decarboxylase 65 (GAD65), insulinoma-associated protein (IA -2, and IA -2 and major diagnostic and predictive mareers in type 1 diabetes (1, 2).
A high-ranking candidate to become a diagnostic marker for a major pathological subtype of FTLD is the transactive response DNA binding protein of 43 kDa (TDP-43).
The major diagnostic techniques for HCC include serum markers, various imaging modalities, and histologic analysis.
The observed increase in the levels of ALT, AST, GGT, and ALP is the major diagnostic symptoms of liver dysfunctions, and these enzymes have been used as markers for monitoring chemically induced tissue damages [ 23].
Changes in DNA methylation have been widely reported in cancer cells, are believed to play a major role in cancer cell behavior, and are the target of current drug and diagnostic marker development efforts [ 8].
Human chorionic gonadotropin (hCG) is a key diagnostic marker of pregnancy.
In the last decade, it has undergone a major transformation, sparked by the landmark discovery of the central role of activating KIT mutations in its pathogenesis and recognition of KIT protein expression (CD 117) as a reliable diagnostic marker of disease.
Tubercular uveitis poses a major diagnostic challenge in endemic countries.
Apnea and brain stem testing are the major diagnostic approach.
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