Sentence examples for major developmental defects from inspiring English sources
Homozygous null mutants are viable and fertile and have no major developmental defects.
The present kit is a compromise, as it still has a substantial number of Dfs that cause major developmental defects.
Importantly, the Soat1 mice learnt and had normal 1-day memory suggesting that they had no major developmental defects.
Ci-E z) morphants exhibited major developmental defeCi-E zlastomorphantssion was impairexhibitedng to the developmajorof a developmentalembryo.
Unexpectedly, mcu knockout in the mouse results in a rather mild phenotype with overall size reduction, decreased effort capacities and metabolic alterations, but no major developmental defects.
Mice deficient for both Mt1 and Mt2 are viable and show beside their greater sensitivity to metals no major developmental defects [ 36, 37].
While in situ hybridization depicts C3G expression in embryonic CNS, somatic and visceral muscles, our analysis of Drosophila C3G mutant embryos has failed to reveal any major embryonic developmental defects in any of these tissues.
Facial clefting generally encompasses a wide range of severity, ranging from minor anomalies such as a bifid (split) uvula, to a cleft lip and palate, to major developmental and structural defects of the facial bones and soft tissues.
Deficiencies in matrix composition and architecture correspond with the onset and progression of developmental defects and major diseases including cancer, fibrosis, and skeletal dysplasias.
This recapitulates the salient phenotype of unc-51−/− mutants, and argues that defective kinesin-mediated transport is the major molecular process that underlies the developmental defects in the unc-51 mutants.
These findings demonstrate the simultaneous occurrence of (a) developmental defects of neuronal growth in three major components of the limbic system, the entorhinal cortex, hippocampus and amygdala, and (b) focal developmental defects of neuronal migration and microdysgenesis in several subdivisions of the hippocampal formation and amygdala, which might be etiologically linked.
