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CTCF has been implicated as a major determinant controlling HSV-1 latency.
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To model the major determinants controlling urban development, three agent groups are defined, namely developer agents, government agents, and resident agents.
In this study, we couple game theory with an integrated agent-cellular method to develop a model of the major determinants controlling urban development, which not only accounts for socioeconomic driving forces but also captures human actions.
This indicates that major determinants controlling antifungal potency as well as morphogenicity reside within the γ-core motif of each defensin.
Indeed, Dicer1-null ES cells phenocopy telomere defects of DNMT-deficient cells, suggesting that Rbl2 and the miR290 cluster are major determinants controlling DNA methylation in ES cells (Gonzalo et al, 2006; Benetti et al, 2008a).
For example, a single C-to-G point mutation in a non-coding RNA, osa-smR5864w, is a major determinant in controlling the pollen fertility or sterility in rice (Zhou et al. 2012).
The major determinant that controls the secretion of cortisol is corticotropin (adrenocorticotropin; ACTH).
The concept that historical glycaemic control is a major determinant of diabetes control, known as metabolic memory or the 'legacy effect', has recently been reported for autonomic neuropathy in the Epidemiology of Diabetes Interventions and Complications study [ 12].
I have always been sceptical of the idea that free diffusion is a major determinant of metabolic control, and these emerging studies simply reinforce my scepticism.
The extracellular signal-regulated kinase (ERK) signaling pathway is a major determinant in the control of diverse cellular processes, such as proliferation and survival, and together with the PI3K/Akt pathway is often up-regulated in many cancers.
Since mealtime insulin dose is a major determinant of postprandial glycemic control, improving the insulin algorithm is a significant clinical issue.
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