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The phrase "major contribution of" is grammatically correct and can be used in written English.
It is often used to indicate a significant or important contribution made by someone or something. Example sentence: The major contribution of Dr. Smith's research was the development of a groundbreaking new treatment for cancer.
Exact(60)
This can be a major contribution of creative staff workers.
"Christine's research suggests that the major contribution of flambé is to look spectacular," said Sacks.
The semi-analytic solution is the first major contribution of the thesis.
Hybridization is a major contribution of VB theory to the language of chemistry.
Major contribution of scale control concentrates on understating the conditions scale formation and its inhibition.
Unbridled eroticism "could well be the major contribution of the Aquarian revolution to human happiness," Comfort wrote.
A major contribution of the Gulf Stream system is its warming effect upon the climates of adjacent land areas.
Use of the latter constitutes a major contribution of this work.
The major contribution of this work leads to successful development of earbud earphone.
Another major contribution of this research is the significant potential for supporting spatial queries.
The major contribution of the present study can be outlined as follows.
More suggestions(16)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com