"major contrast" is correct and usable in written English.
You can use it when you are referring to a substantial difference between two things. For example, "The colors red and blue provide a major contrast in this painting."
This served as a major contrast to Trump's fiery and often bombastic tone on the campaign trail.
Although the major contrast is between the rainy season and the drier months, three seasons may be identified.
Her eye is on Germany's internal politics, its loose federalism and coalition government, a major contrast to France's centralized, nearly monarchical state.
The global paleoclimate was effectively driven by major contrast in the proportions of land and water between the Northern and Southern hemispheres.
That was a major contrast with his predecessor as president, Cristina Fernández, who refused to negotiate with hedge funds that rejected the country's 2005 and 2010 restructurings, which offered about 30 cents in the dollar.
Major contrast enhancement (arrow in c).
With the establishment of the Chosŏn dynasty in 1392, two major, contrasting themes emerged in Korean literature.
The findings give a more detailed profile of who a Guardian reader was, and highlight some of the major contrasts in the different regions.
The states of the glottis, places of articulation, and manners of articulation discussed above are sufficient to distinguish between the major contrasts among the consonants of English and many other languages.
U/Pb TIMS and SHRIMP data document a complex igneous and metamorphic history, with major contrasts between the Rae Province, Chipman domain, and Hearne Province.
This has remained one of the major contrasts between the two schools of linguistic thought over the years, though SFL could be said to occupy the middle ground between T-G and some varieties of 'corpus linguistics' in this respect.
