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For application in developing countries, decentralized systems major constraints include low cost, ease of use, environmental sustainability, reduced maintenance and independence from energy sources.
It also criticises the Palestinian Authority, saying "major constraints include a shortage of clear political direction, limited popular support, management deficiencies, inadequate staffing in key areas, corruption, and accusations of misuse of funds and sponsoring terrorism".
Major constraints include: (i) lack of knowledge and information on principles and methods of organic agriculture; (ii) lack of knowledge on the regulations and requirements for export of organic products; and (iii) lack of market information.
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I agree with Hoang et al. highlighting three major constraints – including financial constraints, supply-side constraints and ongoing epidemiological transition.
In the channel open state, our results identify two major constraints which include an interaction between two I227 of two adjacent S4 segments as well as between C136 in S1 and R228 in S4 of two neighboring VSDs (see model below).
Those constraints include capital limitations, finite labor, or scarce resources.
The tuberculin skin test (TST), the only available method to identify LTBI for more than a century, is known to have major constraints [ 3], including a reduced sensitivity in HIV-infected patients as compared with the general population, particularly in those with low CD4 cell counts [ 4].
In this study the major problems pertained to various facets of human resource constraints including inadequate number of personnel being involved in the supply chain, staff being inadequately trained and staff being inadequately remunerated.
But there are constraints, including political opposition.
Surveys from the physicians' perspective in other clinical settings (mainly oncology) also identified time constraints, including time required to obtain informed consent [ 16, 3] and difficulties including eligible patients [ 16] as a major barrier for patient recruitment.
There was a consensus among the interviewees that the major constraints for using BIM included lack of demand from clients, lack of knowledge, and cost versus benefits issue.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com