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Nevertheless, the major conclusion, which is that RFC does not dissociate after loading PCNA and can unload the clamp from DNA, runs counter to the prevailing view and therefore increases interest in the paper.
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A final part summarises the major conclusions which indicate conclusively that the polymer is irreversibly damaged in the decompression process adopted in the current study.
Two major conclusions, which are typical of the mammalian L1 elements, are apparent: First, in mammals, CpG is a preferred site of cytosine methylation and the methylated cytosine over time is deaminated at a high frequency to form TpG (or CpA), resulting in loss of CpG islands.
Although we cannot exclude that PKCε contributes to phorbol ester potentiation of release, it seems unlikely that novel PKCs, including PKCε, play a major role during PTP, a conclusion which agrees with the inefficiency of PLC inhibitors.
12 There is another form of conclusion which is not actually identical with the major premise, but has the same force: "Death is nothing to us, for that which is dissolved into its elements is devoid of feeling, and that which is devoid of feeling is nothing to us". There is a third form in which the major premise and the conclusion are different.
The major premise can be deduced from other universal premises about animals, and the minor premise, unlike the conclusion which must be inferred, can be known by observation.
His conclusion — which the Yankees now embrace — was that teams generally double their investment in the draft based on the production of players in their first few major league seasons.
Another major conclusion pertains to the mechanisms by which secretions exert their effects on monocytes.
We agree with the reviewers that our work demonstrates that, unlike what we previously believed, Nasonia is not a strict long germ, indicating that these two mechanisms do appear to co-exist, which is the major conclusion of our paper.
Insect embryogenesis comprises a spectrum of short-germ to long-germ, and, although insects like Nasonia and Apis can be called long germ, they are less completely so than Drosophila, indicating that these two mechanisms do appear to co-exist, which is the major conclusion of our paper.
2. Running time evaluations: Another major conclusion of the paper concerns run times, which the author reports in a separate section (3.2).
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