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[18F]FLT imaging is useful particularly in the differentiation between tumour and inflammation, a major concern given the majority of oesophageal cancers will develop on a background of Barrett's oesophagus [19].
Mr. Sondheim declined to comment for this article, but other theater artists said that estate management was a major concern given that artists' legacies would be at stake.
Both he and the Film Expo organizers say that there is occasional overlap in what is screened but that it is not a major concern given the distance between the sites, about 35 miles.
While Van Gaal was pleased that his players found a way past a well-organised Yeovil side, the fresh injuries are a major concern, given United have been without so many players in defence this season.
However, scientists warn that the current low birthrate is a major concern given that it is combined with an increase in mortalities, a situation that presents a significant risk to the species.
Assessment of physical capacity is a major concern, given the increasing prevalence of chronic disabling conditions due cardiovascular disease, usually associated with an intolerance to effort leading to reduced physical activity.
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Especially the scalability and performance of such systems raise major concerns, given the massive amount of spatio-temporal data to be processed.
Air pollution has become a major environmental concern given the ever increasing levels of particulate matter (PM) and the increased in treatment-resistant bacterial and viral strains.
"The growing number of these attacks is a major cause for concern, given that these criminal gangs are able to hit retailers and bank branches in every part of Northern Ireland," he added.
He pointed at the "crackdown" on independent volunteers' activities by the Greek authorities and EU border security agency, including the arrest of the Spanish and Danish volunteers, as a major point of concern, given the large number of people rescued at sea by these groups.
In many ways it is the region of Africa which gives major causes for concern, given the low levels of consumption and the strong growth in projected population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com