Size - Not usually a major concern because the vast majority of guitar straps are adjustable, but you'll still want to be sure the strap is at least long enough to allow comfortable playing while standing up.
Sensor network coverage is a major concern because it reveals how well an area is monitored.
That's a major concern because of the potential to cannibalise book sales.
Today, chemicals that affect hormones – so-called endocrine disruptors – are a major concern because of their prevalence in the environment.
However, the target selectivity is a major concern because most described kinase inhibitors target the highly conserved ATP-binding pocket.
Chlorpyrifos is of major concern because it causes some ten thousand fatalities each year, mostly due to suicidal attempts.
It's a major concern, because the villain looks to be very much front and centre for the sequel.
Security has been a major concern because some earlier versions of Windows – especially XP – were very insecure.
The presence of actinides in radioactive wastes is of major concern because of their potential for migration from the waste repositories and long-term contamination of the environment.
Rapid increase of urban sprawl in many countries worldwide has become a major concern because of its detrimental effects on the environment.
The injury prevents him from throwing, a major concern because the Giants need to reach the 53-man roster limit by Saturday.
