Sentence examples for major codons and from inspiring English sources

We studied the relation between the RMCU of amino acids that have major codons and the two measures of expression.

By the above properties Arg2, Arg4, Glu, Leu2, and Lys do not have major codons and are excluded from the analysis.

Furthermore, we observe that the association between major codons and evolutionary conserved sites is strongest in the most highly biased genes.

We examined the strength of association between major codons and conserved amino acid positions to test for the presence of selection for translational accuracy.

From these counts, an odds ratio test, denoted as ψ, can be computed that gives the magnitude of the association between major codons and evolutionary conserved amino acid positions.

We suggest that, in the first group of amino acids, selection acts to enhance translation efficiency in highly expressed genes by preferring major codons, and acts to reduce translation rate in lowly expressed genes by preferring non-major ones.

Major codon and amino acid preferences under high expression point toward adaptation for translational accuracy and/or efficiency (Akashi 2001; Akashi 2003).

A total of 1887 genes had ψ > 1, meaning there was a greater likelihood of observing an association between a major codon and conserved site than observing an association of a minor codon at a variable site.

The association between the major codon and the anticodon of the most abundant tRNA has been documented in Escherichia coli [ 16, 17], Saccharomyces cerevisiae [ 18], and other species and organelles [ 15, 19- 22].

For instance, Escherichia coli cells starved of asparagine tend to misincorporate lysine when minor asparagine codons are used instead of major codons (Precup and Parker 1987).

The strength of association between conserved sites and major codons for an amino acid can be computed as an odds ratio, denoted here as ψ (Drummond and Wilke 2008; Porceddu et al. 2013).