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Some smoldering-type ATL cases were distributed in the 50% < CADM1+ area and all cases showed a major clone pattern.
All but one of the chronic ATL cases were distributed in the 50% < CADM1+ area and showed a major clone pattern (Fig. 2b, right).
In the 25% < CADM1+ ≤ 50% area, AC and smoldering-type ATL cases were intermingled and all cases showed an oligoclonal or major clone pattern (Fig. 2b, left).
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In the second category, one of several major clones in DCIS became the dominant clone in the invasive tumour, whereas in the third pattern, the major clone in DCIS became one of two major clones in the invasive tumour.
For subtype classification, major clones and scoring patterns were taken into account, with the exception of specimens with overall low scores (<20% cells with any specific aberration) where classification was based solely on tabulated scores.
The oligoclonal state was defined as a ladder-like band pattern without dominant bands, and the major clone state was defined as one or more dominant intense bands.
The fourth pattern was characterized by a shift in the major clone between DCIS and invasive carcinoma [ 63].
The observed band patterns were classified into "polyclonal," "oligoclonal" and "major clone" states according to the number and density of clonal bands.
Compaq, Zenith, Tandy and other major clone makers still support the AT bus.
S-3 and S-4 had similar PVL (S-4: acute, 33% PVL) but exhibited different clonality patterns: oligoclonal for S-3 (three or four relatively large clones at the top surrounded with other clones) vs. monoclonal for S-4 (a large major clone surrounded with some small clones in the background).
CC92 was the major clone spreading in our hospital.
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