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Type-B reactions, therefore, represent a major clinical problem [7].
Management of infection is a major clinical problem.
Critical limb ischemia is a major clinical problem.
Marginal integrity is a major clinical problem in restorative dentistry.
Headache disorders are a major clinical problem, and should be a public health priority.
Local cancer recurrence after "curative" treatment remains a major clinical problem for most cancers.
Study objective: Acute rejection (AR) of the allograft is a major clinical problem after lungtransplantation.
Defective bone healing is a major clinical problem.
Drug resistant typhoid fever is a major clinical problem globally.
Considered to be the "holy grail" of dentistry, regeneration of the periodontal ligament in humans remains a major clinical problem.
However, resistance remains a major clinical problem.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com