Sentence examples for major clinical issue from inspiring English sources

The occurrence of brain metastasis is a major clinical issue.

Obviously, for these patients the major clinical issue would be to rule out cancer.

Identification of patients with high-risk of recurrence is therefore a major clinical issue.

Resistance to chemotherapy remains a major clinical issue in the treatment of colorectal cancer (CRC).

Resistance to chemotherapy remains a major clinical issue in the treatment of colorectal cancer (CRC) and other cancers.

The history of multiple tumors, that is, whether they derive from a common precancerous or cancerous ancestor or individually from hepatocytes, is a major clinical issue.

Here we report only major clinical issues concerning the management of advanced non-small-cell lung cancer (NSCLC).

Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists and internists.

These harms were rare and mild, and unlikely to be major clinical issues.

Nutrition and gastrointestinal function are also major clinical issues in RTT, and there is marked growth failure in most affected individuals (Tarquinio et al., 2012).

Packaging defects were one of the major clinical issues reported, and these included incorrect labelling (ie, wrong drug name, strength or expiry date) and packaging that lacked important information regarding safety or the use of medicines in the patient information leaflets.