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As major clinical causes leading to ARDS, a differentiation was made between pneumonia, sepsis of extra-pulmonary origin, trauma, immunodeficiency, and 'acute on chronic' (i.e., patients with a pre-existing chronic pulmonary disease with acute exacerbation).
Being major clinical causes leading to ARDS, we differentiated between pneumonia, sepsis of extra-pulmonary origin, trauma, immunodeficiency and "acute-on-chronic" (i.e., patients with a preexisting chronic pulmonary disease with an acute exacerbation), as described previously [16].
Major clinical causes of deaths in survivors were congestive heart failure, acute myocardial infarction and sudden death (65%).
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The major clinical effects caused by the venom of this species include vomiting, abdominal pain, diarrhoea, and dizziness.
Bacterial infections are among the major clinical complications causing relatively high-mortality rates after implantation of medical devices.
The major clinical diseases caused by these two genera include Lyme disease, relapsing fever and syphilis [ 18].
Apart from gastroenteritis, wound infections and septicemia are the other major clinical manifestations caused by pathogenic strains of V. parahaemolyticus.
Traumatic brain injury (TBI) is a major clinical problem that causes substantial mortality rates and a broad spectrum of mental disorders.
Despite these advances, these cancers remain major clinical problems by causing considerable morbidity and mortality in women worldwide.
Bone metastases are a major clinical concern and cause severe pain, pathological fractures, spinal cord compression, hypercalcaemia with a significant decrease in quality of life [ 3].
Harms are few and unlikely to cause major clinical problems.
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