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Another major clinical application of single-cell sequencing will be in the genomic profiling of copy number or sequence mutations in CTCs and disseminated tumor cells (DTCs).
The repair of bone defects by tissue grafting is a major clinical application of cell-based therapies in modern orthopedic and maxillofacial surgery.
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Pangenomic studies identified distinct molecular classes for many cancers, with major clinical applications.
Wavefront-guided excimer laser refractive surgery and new customized intraocular lens and contact lens designs are major clinical applications of corneal wavefront analysis.
The major clinical applications for cardiac MRI at this time include imaging of structural morphology and myocardial evaluation.
Major clinical applications include risk assessment and stratification.
Tumour antigens identified by SEREX or similar techniques have two major clinical applications.
To date, the major clinical applications of SERMs are their use in the prevention and treatment of breast cancer, the prevention of osteoporosis, and maintenance of beneficial serum lipid profiles in postmenopausal women.
In our study, HIF-1 α inhibition was achieved using topotecan, a topoisomerase I poison with major clinical applications in the management of ovarian and small cell lung cancer.
Consequently, its current major clinical applications are the acceleration of neutrophil reconstitution after myelo-suppression and the mobilization of bone marrow HSC 6. G-CSF also induces expansion 7– 9 and enhancement of phagocytosis 8 of the monocyte/macrophage system.
To date, the major clinical applications of SERMs are their use in the prevention and treatment of breast cancer, the prevention of osteoporosis, and the maintenance of beneficial serum lipid profiles in postmenopausal women.
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