Sentence examples for major clade replacement from inspiring English sources

This finding supports the hypothesis that major clade replacement events can be driven by natural selection and emphasizes the potentially important role of vector-virus interactions in DENV evolution [ 178].

By comparing the ability of DENV-1 isolates from Thailand, spanning a 24-year period, to infect and be transmitted by St. aegypti, Lambrechts et al. found that a major clade replacement event in the mid-1990s wassociatedted with a higher transmission potential of the isolates belonging to the new clade.

The appearances of rare isolates such as D1.Malaysia.92844/91, D1.Malaysia.10837/97, D1.Malaysia.32581/04, D1.Malaysia.32858/04 and D1.Malaysia.296236/11 could represent the potential clade replacement candidates for the future major outbreaks.

DENV-1 clade replacement is associated with recurrences of major DENV-1 outbreaks in Malaysia.

DENV-1 clade replacement is associated with the recurring major DENV-1 outbreaks in Malaysia.

The genotype I viruses from the 1987 , 1997and 2004 outbreaks grouped into clade Ia, Ib and Ic, respectively in a ladder-like topology suggesting temporal clade replacement occurred in each of the major DENV-1 outbreak.

Interestingly, the clade containing L. borgpetersenii isolates split into one major clade designated as G1 and a minor clade, G2.

They mostly shared the mtDNA haplotypes of the major clade (A) and one of the two minor clades (B).

This unique clade replacement was complete just before DENV-3 emerged.

This tree showed one major clade and six internal branches.

In each major clade, additional minor clades of closely related nests were indicated, two in each of the Melbourne and Perth clades and one in the Adelaide clade.