Sentence examples for major checkpoint for from inspiring English sources

Cell cycle progression through G1 phase into S phase is a major checkpoint for cells during proliferation.

It is known that the G1/S phase transition is a major checkpoint for cell cycle progression.

Heterologous complementation experiments showed that the idiosyncratic properties of the 4E and iso4E proteins create a major checkpoint for viral infection of different hosts.

G1/S phase transition is a major checkpoint for cell cycle progression and cyclin D1-CDK6 complex is one of the critical positive regulators during this transition [ 26, 27].

A high concentration of GlcNAc, perhaps mimicking its accumulation after autolytic degradation of the vegetative mycelium, may be a major checkpoint for the onset of secondary metabolism (Rigali et al. 2008).

In contrast, the recent study on E. coli RNAP suggested that the open state of the active centre (with unfolded TL) may be a major checkpoint for discrimination against ncNTPs and c2'dNTPs [ 13].

Thus, the translation of Pdk1 serves to slow a major checkpoint of oxidative metabolism.

We propose that the major checkpoint role for Bub1 is as a signalling scaffold.

Eukaryotic cell proliferation is primarily regulated by cell cycle, wherein G1/S transition is a major checkpoint responsible for initiation and completion of DNA replication.

In this strain, regulation of the two major checkpoint targets required for preventing mitosis, Cdc25 and Mik1, is disrupted [12].

Cells deficient for Mec1p, the yeast ATR equivalent and the major checkpoint kinase in yeast, have a very modest decrease in telomere length (Ritchie et al. 1999).