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While the Intel Corporation, the developer of P.C.I., has tweaked the standard to support faster processors over the years, major changes were hampered by technical and cost limitations, Mr. Zucker said.
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Several major retailers have high debt, and I believe that their ability to make much-needed change is hampered by lack of "loose change" to invest in new ideas.
Major changes were proposed.
No major changes were made.
No major changes were necessary.
Major changes are on the horizon.
For the major media conglomerates that were hampered by both the economic recession and technology-driven changes in consumer habits, the world is starting to look brighter.
Another major change was comedy itself.
However, if there are obstacles in any of these streams, substantial change will be hampered.
These changes would have been hampered by a layer of operating control from the U.S. parent.
However, the capacity to introduce specific directed changes at given loci is hampered by the fact that the major cellular repair pathway that occurs following Cas9-mediated DNA cleavage is the erroneous non-homologous end joining (NHEJ) pathway.
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CEO of Professional Science Editing for Scientists @ prosciediting.com