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The party's dominant far right ideologues tried hard to prevent any compromise with Democrats, voting overwhelmingly to oppose a combination of deep budget cuts and extensions of 2009's temporary tax hikes even if major changes were effected on public pensions and regulations and state spending limits were put in place.
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Under the Tudors, though it was still possible to make law by royal proclamation, the monarchs rarely resorted to such an unpopular measure, and all major political changes were effected by acts of Parliament.
Nationwide, two major changes were put into effect yesterday at postal stations.
The effects of mutating these Phe residues differed strongly from effects of mutating F427, where major changes were seen in both single-channel conductance and protein translocation.
Major changes were proposed.
No major changes were necessary.
No major changes were made.
Among adults, no major changes were observed.
The change will be effected tomorrow morning.
Therefore, a major challenge for educators is effecting knowledge transfer and behaviour change.
These changes are more than jargon, cliché, and hyperbole, and they are effecting major transformations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com