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This creates major challenges with respect to care quality, safety, and cost.
One of the major challenges with the translation of PEF technologies to clinics is muscle contraction.
One of the major challenges with ocean racing is that the boat needs to be manned 24 hours a day.
One of the major challenges with smoking cessation in CCSs is how to reach such a geographically dispersed population.
"One of the major challenges with this museum was to link it with the surroundings," Mr. Calatrava said on the phone from his home in Zurich.
Austin faces major challenges, with decisions pending on how to respond to Iran's nuclear programme, and also whether the US becomes drawn into the Syria conflict.
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The other major challenge with electric vehicles is the cost of the battery packs.
From Putin's point of view, he has a major challenge with terrorism.
Aid workers said both were a major challenge, with supplies and relief workers overstretched.
The major challenge with such dynamic models is to guarantee liveness and boundedness.
However, operation under high load and low load conditions is a major challenge with RCCI combustion.
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