Sentence examples for major challenge owing from inspiring English sources

However, designing of functional chemosensors for recognition of anions is a major challenge owing to different parameters such as larger size and varying geometries.

Setting conditions for the avoidance of in-service crack growth in aggressive corroding environments has long been a major challenge owing to the number of variables that have a significant effect on material behaviour.

The effective treatment of breast cancer remains a major challenge, owing to the recurrence of treatment-resistant tumours.

Implementation of network coding on mobile platforms poses several major challenges owing to their limited memory, energy, and computational power.

However, generating fully functional cells from hESCs and achieving this goal using clinically-compatible conditions remain major challenges owing to the presence of undefined serum and cellular components in standard culture media and differentiation protocols.

As indicated by the European Union's 2012 Commission Action Plan for the EU Health Workforce, the health sector faces major challenges, owing to labour shortages, attrition and relatively low pay in some health occupations.

Life-threatening fungal infections represent a major contemporary challenge owing to their increasing occurrence and the emergence and re-emergence of outbreaks [2], [16], [29], [30].

2 However, despite enormous progress in the aldol addition arena, its application to the synthesis of tertiary alcohols still remains a major challenge, principally owing to a lack of reactivity and the fact that the differentiation of the enantiotopic faces is more difficult with ketone electrophiles than with the corresponding aldehydes.

However, implementation of LSPR bionanosensing in cellular functional immunoanalysis based on a cytokine secretion assay poses major challenges primarily owing to its limited sensitivity and a lack of sufficient sample handling capability.

The development of small molecule drugs targeting protein protein interactions (PPI) represents a major challenge, in part owing to the misunderstanding of the PPI chemical space.

The acute form of the disease is mostly observed within the first 100 days post-transplantion, and is a major challenge to transplants owing to associated morbidity and mortality [ 1, 5].