Sentence examples for major cellular uptake from inspiring English sources

Therefore, the major cellular uptake mechanism for the peptide-conjugated NPs should be endocytosis.

For example, DCT1 (divalent cation transporter-1; also known as NRAMP2 or DMT1) is considered to be a major cellular uptake mechanism for Fe(2+) and other essential divalent metals, but this protein also mediates uptake of Cd(2+), Pb(2+), and possibly of other toxic divalent metals.

The actual composition of the formed protein corona might be of major importance for cellular uptake of magnetic nanoparticles.

At the present, several renal membrane transporters have been cloned and identified [ 15], and among these, organic anion transporter 3 (Oat3: SLC22A8) is highly expressed [ 16] and plays a major role in cellular uptake of organic anions across the basolateral membrane of renal proximal tubules.

First major limitation is the cellular uptake of the polyplexes.

Walkey and colleagues demonstrated that AuNPs not grafted with PEG ("bare AuNPs") or grafted with different densities of PEG exhibited major differences in the cellular uptake and intracellular agglomeration state [22].

One major obstacle is their inefficient cellular uptake and poor accessibility to target sites.

Cellular uptake of the major trypanocidal drugs is thought to occur through an adenosine transporter.

We found that the myotubes exhibit changed expression of key regulators for the uptake and utilization of two major cellular fuels, glucose and lactate.

The SLC superfamily is a major group of membrane transporter proteins that control cellular uptake and efflux of nutrients, neurotransmitters, metabolites, drugs, and toxins [28].

Improvement of cellular uptake and subcellular resolution remains a major obstacle in the successful and broad application of cellular optical probes.