Sentence examples for major cellular target from inspiring English sources

They are also the major cellular target for the immunosuppressive drug Cyclosporin A (CsA).

It has been shown in clinical observations from SARS-infected patients' samples that the respiratory tract is the major cellular target for infection and replication [28], [29].

Myosin IIA appears to be a major cellular target of mts1 [45], the small calcium-binding protein metastasin-1, and co-localizes with mts1 to the leading edge of migrating cancer cells [46]; mts1 influences both the assembly behavior of myosin IIA and its phosphorylation [47], [48].

In this respect, mast cells, that constitute a major cellular target of IL-33 [5] [75]–[7] and are strategically positioned closed to vessel walls and epithelial surfaces exposed to the environment (including the skin and gastrointestinal tract) [28], could play an important role in the response to the IL-33 'alarmin' signal released by damaged endothelial or epithelial cells.

A major cellular target of metastasin-1 seems to be myosin IIA (Garrett et al, 2006).

Previous studies identified the transcription factor NF-κB as the major cellular target of StpC.

Endosomal-lysosomal system and mitochondria are the major cellular targets of ENMs.

The major cellular targets of UV-C are various biomolecules, which directly absorb this radiation or are indirectly affected by various UV-C induced photochemical reactions.

The major cellular targets of NFκB are chemokines, immune receptors, adhesion molecules, stress response genes, regulators of apoptosis, transcription factors, growth factors, enzymes and cell cycle regulators.

The major cellular targets of UV-C are different biomolecules, which directly absorb this radiation, or which are indirectly affected by various UV-C induced photochemical reactions (Charles [2008]).

CsA is known to have three major cellular targets: cellular cyclophilins (CyPs), calcineurin (CN), and transporters including MDRs and MRPs.