Sentence examples for major cellular defects from inspiring English sources

We have recently developed a human stem cell model by homozygous depletion of the exons 15 and 16 of WRN alleles, which recapitulates the major cellular defects of WS, including accelerated senescence, growth arrest, telomere attrition, increased DNA damage response, excessive production of inflammatory factors, as well as increased stem cell attrition in the in vivo niche (Zhang et al., 2015).

TbBiP and TbSec61 knockdown led to rapid and major cellular defects, consistent with central roles in folding and translocation pathways.

Thus, msj-1 mRNA has also been detected in the central nervous system, at ventral horn motoneuron levels [ 74], the other major site of cellular defect in the wobbler mice.

Our study identifies Oxr1 as a modifier of three major cellular pathological features of ALS associated with Fus and Tdp-43 mutations: mis-localization and aggregation of mutant proteins, splicing defects and mitochondrial abnormalities.

So far the major cellular companies have not said whether they have any interest.

With all the major cellular carriers offering child locator features, we wonder how committed Disney is to being in the cellular business, particularly as losses begin to mount".

OTHER NEWS KOMMERSANT CHECHNAY'S CELLULAR CONNECTION MORE ACCESSIBLE: Megafon, a major cellular operator, halved its tariffs in Chechnya in a deal that took two weeks to negotiate.

The underlying cellular defects appear to be related to improper neuronal migration during early prenatal development.

(Similar services are available from all major cellular networks).

And the corporate bragging rights that come with controlling a major cellular operator in the United States are a powerful draw.

Proteins, the major cellular component, are naturally the major targets of free radicals.