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Mesenchymal stem cells (MSCs) and chondrocytes are the two major cell sources for cartilage tissue engineering.
Chondrocytes, a major cell sources for cartilage tissue engineering, also express the H4 receptor.
Combined use of antibodies for such molecules and cell type-specific markers can identify the major cell sources and examine cell phenotypic changes (e.g., differentiation, activation).
It is widely agreed that macrophages and dendritic cells are the major cell sources contributing to the rapid release of IL-23 during disease.
Table 1 Sources and biological effect of investigated inflammatory mediators Inflammatory mediator Abbreviation Major cell sources Major activity Interleukin 6 IL-6 T cells, macrophages Mediator of fever and acute phase response.
Undoubtedly, the major cell sources are the immunocompetent cells, but urothelial cells contribute to a significant degree.
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In amphibian limb regeneration (i.e., newt and axolotl), it is the multipotent stem cells which are generated via the dedifferentiation of myofibers that are the major cell source for "blastema" formation and consequently "perfect" limb regeneration [11].
The major cell source of H MGB1 production in myositis seems to be the mononuclear inflammatory cells.
As the major cell source in the stroma and a long-lived cell system, fibroblasts are able to accumulate aging-associated alterations and consequently adapt their cellular functions.
As the major cell source in the dermis and a long-lived cell system, dermal fibroblasts are able to accumulate aging-associated alterations and adapt their cellular functions.
Interleukin (IL -17 and IL -17jor cell source, the type 17 T helper cells (Th17), hand been itslicated in the pathogenesis of various inflamajorry diseases [ 10, 11].
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