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In spite of the major cell loss, regression came to a halt after about 10 days.
Whether neural cell death plays a role in MDD is controversial because there is no major cell loss or neuropathology found in postmortem tissues of MDD patients (Czéh and Lucassen, 2007; Krishnan and Nestler, 2008).
Given the lack of cell supply in cartilage, major cell loss in cartilage and neocartilage will inevitably lead to tissue failure, as chondrogenic cells are the only source of matrix synthesis in theses tissues.
This could have very important physiological implications since removal of apoptotic cells is likely to be the most important event in vivo if tissue structure and function are to be maintained in the face of major cell loss [ 23].
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First, after injection into beating myocardium, mechanical leakage and washout may account for a major portion of cell loss after cell implantation [17].
Aging is a complex multifactorial process, whereby organisms undergo major cell degeneration and loss of function.
Identification of disordered glucose metabolism before major β-cell loss may be beneficial, since early insulin therapy improves lung function and reduces the number of acute respiratory infections (4, 5).
In the Du145 line, lack of adhesion was the major factor leading to cell loss.
This study confirmed that CMV is a major cause of corneal endothelial cell loss in patients with hypertensive anterior uveitis.
As none of the major DRG subpopulations displayed preferential cell loss in Kidins220−/− mice, we suggest that Kidins220 acts as a general survival factor during the early stages of sensory neuron development.
These data suggest that loss of the major cell envelope component SL-1 does not compromise the overall integrity or permeability of the Mtb cell envelope in vitro.
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